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‘CRISPR Cas9, albeit controversial, is now a booming area of


January 19th, 2018

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Using a technique known as high speed atomic force microscopy, the researchers from the University of Tokyo and Kanazawa University captured a more precise look.This relies on a tiny, fast moving needle which traces the shape of Cas9 as it works, creating a real time video.WHAT IS CRISPR CAS9?CRISPR Cas9 is a tool for making precise edits in DNA, discovered in bacteria.The acronym stands for ‘Clustered Regularly Inter Spaced Palindromic Repeats’.The technique involves a DNA cutting enzyme and a small tag which tells the enzyme where to cut.By editing this tag, scientists are able to target the enzyme to specific regions of DNA and make precise cuts, wherever they like.The CRISPR/Cas9 technqiue uses tags which identify the location of the mutation, and an enzyme, which acts as tiny scissors, to cut DNA in a precise place, allowing small portions of a gene to be removedIt has been used to ‘silence’ genes effectively switching them off.When cellular machinery repairs the DNA break, it removes a small snip of DNA.In this way, researchers can precisely turn off specific genes in the genome.The approach has been used previously to edit the HBB gene responsible for a condition called thalassaemia.’Using HS AFM, we visualized the real space and real time dynamics of CRISPR Cas9 in action, thereby improving our mechanistic understanding of the RNA guided DNA cleavage by Cas9.’CRISPR Cas9, albeit controversial, is now a booming area of research as scientists work to harness the technique to essentially edit out diseases at the gene level.And now, they can finally see what that looks like.Most watched News videos Sanders says Trump book is of false and fake information Trump says ex ally Bannon his tune pretty quick Bouncer attacks man outside Ink nightclub in Nottingham WH: Bannon accusation against Trump Jr. Is and Fury portrays an inept of Trump in the White House Passengers scream in terror as airplane wing bursts into flames Fleet feet! Fennec fox sprints around owner for attention Bannon calls Don Jr Russian meeting in new book Sarah Sanders calls Michael Wolff book fantasy Plane reroutes after passenger smears feces all over bathroom Michael Wolff retweets joke video of Trump his book The White House defends Trump tweet aimed at N KoreaExplosive new book calls Trump ‘chronically’ unfaithful. SEBASTIAN SHAKESPEARE: Sophie Dahl’s 60 year old mother.

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